Week 7 NFL betting odds, spreads, totals, lines for every game, including Bears-Patriots, Seahawks-Chiefs

This page may contain affiliate links. If you click a link and sign up, make a deposit, place a wager, or make a trade, we may earn a commission at no additional cost to you. The Week 7 NFL betting lines, including spreads and totals, are out for every game Oct 21, 2026 at 11:57 am ET • 3 min read The Week 7 NFL odds feature a 14-game schedule beginning Thursday night, when the Chicago Bears host the New England Patriots at Soldier Field. DraftKings lists the Bears as 3-point favorites, with both teams entering at 4-2. The Over/Under for total points scored in Patriots vs. Bills is 50.5. Sunday's schedule includes the Pittsburgh Steelers facing the New Orleans Saints in France, followed by the Detroit Lions hosting the Green Bay Packers in an NFC North matchup. The Houston Texans (-10 vs. New York Giants) are this week's biggest favorite, according to the latest Week 7 NFL spreads. The San Francisco 49ers are listed at -3.5 on the road against the Atlanta Falcons, while the Seattle Seahawks are favored by 2.5 against the Kansas City Chiefs. Bet on every Week 7 NFL game with the latest DraftKings promo code, where new users get $200 in bonus bets plus 3 months of NBA League Pass after making a $5 wager: Below you'll find the NFL betting odds for every Week 7 matchup. You can find the SportsLine Projection Model's NFL betting advice for Week 7 here. Trade $25+ at Kalshi using the best Kalshi promo code CBSSPORTS55 and get a $55 bonus:** Odds provided by DraftKings are subject to change **Thursday, October 22New England Patriots vs. Chicago BearsSpread: Bears -3Moneyline: Bears (-148), Patriots (+124)Total: 50.5Bet on the NFL with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets:Sunday, Oct. 25New Orleans Saints vs. Pittsburgh SteelersSpread: Steelers -3.5Moneyline: Steelers (-180), Saints (+150)Total: 44.5Claim $200 in bonus bets with a $10 bet by signing up for bet365 Sportsbook with the bet365 bonus code CBSBET365:San Francisco 49ers vs. Atlanta FalconsSpread: 49ers -3.5Moneyline: 49ers (-205), Falcons (+170)Total: 50.5Claim the Caesars Sportsbook promo code CBSSPORTSBR250 here and get your bonuses:Cleveland Browns vs. Tennessee TitansSpread: Browns -1.5Moneyline: Browns (-130), Titans (+110)Total: 38.5Trade $25+ at Kalshi using the best Kalshi promo code CBSSPORTS55 and get a $55 bonus:Indianapolis Colts vs. Minnesota VikingsSpread: Vikings -6.5Moneyline: Vikings (-278), Colts (+225)Total: 41.5Bet on NFL games with the latest DraftKings promo code and get $200 in bonus bets and 3 months of NBA League Pass after making a $5 wager: Miami Dolphins vs. New York JetsSpread: Jets -4.5Moneyline: Jets (-230), Dolphins (+190)Total: 38.5Bet on the NFL with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets:Tampa Bay Buccaneers vs. Carolina PanthersSpread: Panthers -3.5Moneyline: Panthers (-192), Buccaneers (+160)Total: 44.5Claim the Fanatics Sportsbook promo code here to get $350 in FanCash:Cincinnati Bengals vs. Baltimore RavensSpread: Ravens -2.5Moneyline: Ravens (-148), Bengals (+124)Total: 51.5Claim the Caesars Sportsbook promo code CBSSPORTSBR250 here and get your bonuses:New York Giants vs. Houston TexansSpread: Texans -10Moneyline: Texans (-520), Giants (+390)Total: 42.5Trade $25+ at Kalshi using the best Kalshi promo code CBSSPORTS55 and get a $55 bonus:Denver Broncos vs. Arizona CardinalsSpread: Broncos -4.5Moneyline: Broncos (-238), Cardinals (+195)Total: 43.5Claim $200 in bonus bets with a $10 bet by signing up for bet365 Sportsbook with the bet365 bonus code CBSBET365:Green Bay Packers vs. Detroit LionsSpread: Lions -3Moneyline: Lions (-166), Packers (+140)Total: 53.5Bet on the NFL with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets:Los Angeles Rams vs. Las Vegas RaidersSpread: Rams -4.5Moneyline: Rams (-225), Raiders (+185)Total: 47.5 Claim the Fanatics Sportsbook promo code here to get $350 in FanCash:Kansas City Chiefs vs. Seattle SeahawksSpread: Seahawks -2.5Moneyline: Seahawks (-135), Chiefs (+114)Total: 42.5Trade $25+ at Kalshi using the best Kalshi promo code CBSSPORTS55 and get a $55 bonus:Monday, Oct. 26Dallas Cowboys vs. Philadelphia EaglesSpread: Cowboys -4.5Moneyline: Cowboys (-218), Eagles (+180)Total: 44.5Bet on the NFL with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets: