Week 6 NFL odds, spreads, totals, lines for every game, including Chargers-Chiefs, Packers-Cowboys

This page may contain affiliate links. If you click a link and sign up, make a deposit, place a wager, or make a trade, we may earn a commission at no additional cost to you. NFL Week 6 continues with Chiefs-Chargers and Packers-Cowboys on Sunday Oct 18, 2026 at 11:31 am ET • 2 min read NFL Sunday has arrived, and the Week 6 NFL odds have seen some noticeable shifts throughout the week. After opening at -1.5, the Eagles are now 3-point underdogs at home against the Panthers after quarterback Jalen Hurts (blood clot) was placed on injured reserve. Panthers vs. Eagles kicks off at 1 p.m. ET. Other notable Week 6 NFL lines include Jets vs. Patriots (-7), Bills vs. Raiders (+5.5), Chargers vs. Chiefs (-7.5) and Cowboys vs. Packers (-1.5). Bet on every Week 6 NFL game with the latest DraftKings promo code, where new users get $200 in bonus bets plus 3 months of NBA League Pass after making a $5 wager: Below you'll find the NFL betting odds for every Week 6 matchup. You can find the SportsLine Projection Model's NFL betting advice for Week 6 here. Trade $25+ at Kalshi using the best Kalshi promo code CBSSPORTS55 and get $55 as a sign-up bonus:** Odds provided by DraftKings are subject to change **Sunday, Oct. 18Jacksonville Jaguars vs. Houston Texans Spread: Jaguars -2.5Moneyline: Jaguars (-148), Texans (+124)Total: 42.5 Claim $200 in bonus bets with a $10 bet by signing up for bet365 Sportsbook with the bet365 bonus code CBSBET365:Atlanta Falcons vs. Chicago Bears Spread: Bears -1.5Moneyline: Falcons (-102), Bears (-118)Total: 52.5 Claim the Caesars Sportsbook promo code CBSSPORTSBR250 here and get your bonuses:Cleveland Browns vs. Baltimore Ravens Spread: Ravens -3Moneyline: Browns (+140), Ravens (-166)Total: 39.5 Bet on the NFL with the FanDuel promo code and get $350 in bonus bets:Indianapolis Colts vs. Tennessee Titans Spread: Colts -7Moneyline: Colts (-340), Titans (+270)Total: 44.5 Bet on NFL games with the latest DraftKings promo code and get $200 in bonus bets and 3 months of NBA League Pass after making a $5 wager: New England Patriots vs. New York Jets Spread: Patriots -7.5Moneyline: Patriots (-340), Jets (+270)Total: 43.5 Bet on the NFL with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets:New York Giants vs. New Orleans Saints Spread: Saints -1.5Moneyline: Saints (-110), Giants (-110)Total: 46.5 Claim the Fanatics Sportsbook promo code here to get $350 in FanCash:Philadelphia Eagles vs. Carolina Panthers Spread: Panthers -3Moneyline: Panthers (-166), Eagles (+140)Total: 39.5 Claim the Caesars Sportsbook promo code CBSSPORTSBR250 here and get your bonuses:Tampa Bay Buccaneers vs. Pittsburgh Steelers Spread: Steelers -2.5Moneyline: Buccaneers (+124), Steelers (-148)Total: 38.5Bet on the NFL with the FanDuel promo code and get $350 in bonus bets:Los Angeles Rams vs. Arizona Cardinals Spread: Rams -12.5Moneyline: Rams (-750), Cardinals (+525)Total: 51.5 Claim $200 in bonus bets with a $10 bet by signing up for bet365 Sportsbook with the bet365 bonus code CBSBET365:Kansas City Chiefs vs. Los Angeles Chargers Spread: Chiefs -7.5Moneyline: Chiefs (-455), Chargers (+350)Total: 41.5 Bet on the NFL with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets:Las Vegas Raiders vs. Buffalo Bills Spread: Bills -5.5Moneyline: Raiders (+185), Bills (-225)Total: 53.5 Claim the Fanatics Sportsbook promo code here to get $350 in FanCash:Green Bay Packers vs. Dallas Cowboys Spread: Packers -1.5Moneyline: Packers (-118), Cowboys (-102)Total: 53.5 Bet on the NFL with the FanDuel promo code and get $350 in bonus bets:Monday, Oct. 19San Francisco 49ers vs. Washington Commanders Spread: 49ers -7.5Moneyline: 49ers (-455), Commanders (+350)Total: 52.5 Bet on the NFL with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets: