Week 5 NFL score predictions, odds, picks, betting advice: Proven model has projections for every game

This page may contain affiliate links. If you click a link and sign up, make a deposit, place a wager, or make a trade, we may earn a commission at no additional cost to you. Make NFL best bets at NFL betting sites by seeing NFL score predictions from our advanced model Oct 11, 2026 at 10:02 am ET • 4 min read You can use the best sportsbook promos to earn more than $3,000 in sign-up bonuses from top betting apps for the loaded Week 5 NFL slate. The action continues on Sunday with Packers vs. Bears, as Chicago is favored by 1.5 on the road, and the over/under is 46.5 points despite the fact that Tyson Bagent will start for the visitors in place of Caleb Williams (hamstring). The Week 5 NFL odds also list Seattle as the 3-point favorite at home in Seahawks vs. 49ers, while the over/under is 46.5.The SportsLine Projection Model simplifies NFL betting with Week 5 NFL score predictions and NFL picks for all Week 5 NFL games by simulating each matchup 10,000 times. Bet on NFL Week 5 with the FanDuel promo code and get $250 in bonus bets:New users can get the latest DraftKings promo code, which offers $150 in bonus bets after your first $5 bet right here: Bet on the NFL with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets:Week 5 NFL betting promos and bonus codes BrandOfferCBS Promo Code DraftKingsBet $5, Get $150 in Bonus BetsJust click hereFanDuelBet $5, Get $250 in Bonus BetsJust click hereBetMGMUp to $1,500 in bonus bets if your first bet losesCBSSPORTSFanaticsBet $20, Get $350 in FanCashCBSFAN350bet365Bet $10, Get $200 in bonus bets, win or loseJust click hereHard Rock BetBet $5, Get up to $500 in No Sweat Bets, win or loseJust click hereCaesarsUp to $250 in bonuses as five days of $50 bet resetsCBSSPORTSBR250Week 5 NFL score predictionsSunday, Oct. 11Packers vs. Bears (-1.5), 1 p.m. ET Score prediction: Bears 25, Packers 24SportsLine predicts that the Packers cover as 1.5-point underdogs in 51% of simulations. Claim the Fanatics Sportsbook promo code here to get $350 in FanCash:Dolphins vs. Bengals (-7), 1 p.m. ET Score prediction: Bengals 27, Dolphins 18SportsLine predicts that the Bengals cover as 7-point favorites in 52% of simulations. Bet on the NFL with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets:Jets (-2.5) vs. Browns, 1 p.m. ET Score prediction: Jets 25, Browns 19SportsLine predicts that the Jets cover as 2.5-point favorites in 58% of simulations. Claim the Caesars Sportsbook promo code CBSSPORTSBR250 and get up to $250 in bonuses as five days of $50 bet resets here:Titans vs. Texans (-7), 1 p.m. ET Score prediction: Texans 27, Titans 18SportsLine predicts that the Texans cover as 7-point favorites in 52% of simulations. Claim $200 in bonus bets with a $10 bet by signing up for the bet365 promo code CBSBET365:Steelers (-3) vs. Colts, 1 p.m. ET Score prediction: Colts 27, Steelers 26SportsLine predicts that the Colts cover as 3-point underdogs in 56% of simulations. Bet on the NFL by claiming the latest DraftKings promo code, where new users get $150 in bonus bets after your first $5 wager: Patriots (-3.5) vs. Raiders, 1 p.m. ET Score prediction: Patriots 23, Raiders 20SportsLine predicts that the Raiders cover as 3.5-point underdogs in 51% of simulations. Sign up at Hard Rock Bet and get up to $500 in No Sweat Bets:Saints vs. Vikings (-1.5), 1 p.m. ET Score prediction: Vikings 25, Saints 20SportsLine predicts that the Vikings cover as 1.5-point favorites in 57% of simulations. Use the FanDuel promo code to get $250 in bonus bets for NFL games:Commanders (-3.5) vs. Giants, 1 p.m. ET Score prediction: Commanders 26, Giants 21SportsLine predicts that the Commanders cover as 3.5-point favorites in 52% of simulations. Claim the Caesars Sportsbook promo code CBSSPORTSBR250 and get up to $250 in bonuses as five days of $50 bet resets here:Chargers vs. Broncos (-3.5), 4:05 p.m. ET Score prediction: Broncos 21, Chargers 18SportsLine predicts that the Chargers cover as 3.5-point underdogs in 52% of simulations. Bet on the NFL by claiming the latest DraftKings promo code, where new users get $150 in bonus bets after your first $5 wager: Cardinals vs. Lions (-5.5), 4:25 p.m. ET Score prediction: Lions 32, Cardinals 26SportsLine predicts that the Lions cover as 5.5-point favorites in 52% of simulations. Bet on the NFL with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets:Seahawks (-3) vs. 49ers, 4:25 p.m. ET Score prediction: Seahawks 26, 49ers 21SportsLine predicts that the Seahawks cover as 3-point favorites in 55% of simulations. Claim $200 in bonus bets with a $10 bet by signing up for bet365 Sportsbook with the promo code CBSBET365:Falcons (-3) vs. Ravens, 8:20 p.m. ET Score prediction: Ravens 26, Falcons 25SportsLine predicts that the Ravens cover as 3-point underdogs in 56% of simulations. Claim the Fanatics Sportsbook promo code here to get $350 in FanCash:Monday, Oct. 12Rams (-3.5) vs. Bills, 8:15 p.m. ET Score prediction: Rams 26, Bills 24SportsLine predicts that the Bills cover as 3.5-point underdogs in 52% of simulations. 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