The 15 movies with the largest opening weekends of all time

"Spider-Man: Brand New Day." Sony/Marvel Superhero fatigue seems not to count when it comes to your friendly neighborhood Spider-Man."Spider-Man: Brand New Day" had a huge opening at the box office, bringing in $360 million its opening weekend, according to Sony, which released the movie. That's the biggest domestic opening weekend ever, beating the prior No. 1, 2019's "Avengers: Endgame," which made $357 million its first weekend.With the help of data from Box Office Mojo, we compiled the top 15 opening weekends ever at the domestic box office.Kirsten Acuna contributed to previous versions of this story. 15. "Black Panther: Wakanda Forever" (2022) "Black Panther: Wakanda Forever." Disney/Marvel Studios Opening weekend: $181.3 millionFollowing the death of King T'Challa, his sister, Shuri (Letitia Wright), takes the Black Panther mask to fight for Wakanda. 14. "Incredibles 2" (2018) "Incredibles 2." Disney/Pixar Opening weekend: $182.6 millionThe superhero family sets out on a new mission with Elastigirl (Holly Hunter) taking the lead and Mr. Incredible (Craig T. Nelson) taking a back seat to take care of the kids. 13. "Doctor Strange in the Multiverse of Madness" (2022) "Doctor Strange and the Multiverse of Madness." Disney/Marvel Studios Opening weekend: $187.4 millionOne of the trippiest Marvel movies ever made, Doctor Strange (Benedict Cumberbatch) finds himself going up against the powers of the multiverse and the Scarlet Witch (Elizabeth Olsen). 12. "Avengers: Age of Ultron" (2015) "Avengers: Age of Ultron" Disney Opening weekend: $191.3 millionTony Stark and Bruce Banner try to jump-start a peacekeeping program called Ultron; things go horribly wrong. 11. "The Lion King" (2019) "The Lion King." Disney Opening weekend: $191.7 millionThis live-action version of Disney's classic 1994 animated movie follows young Simba on his journey to become king. 10. "Black Panther" (2018) "Black Panther." Walt Disney Studios Motion Pictures Opening weekend: $202 millionChadwick Boseman plays T'Challa, the King of Wakanda, a technologically advanced African nation. But his throne is challenged by a vengeful outsider, Killmonger (Michael B. Jordan). 9. "The Avengers" (2012) "The Avengers." Marvel Opening weekend: $207.4 millionEarth's greatest heroes must figure out how to work as a team to stop the mischievous Loki. 8. "Jurassic World" (2015) "Jurassic World." Universal Opening weekend: $208.8 millionA new theme park is created on the site of the original Jurassic Park, leading to chaos as genetically modified dinosaurs escape containment. 7. "Deadpool & Wolverine" (2024) "Deadpool & Wolverine." Walt Disney Studios Motion Pictures Opening weekend: $211.4 millionDeadpool's (Ryan Reynolds) search for Wolverine (Hugh Jackman) leads to a thrill ride filled with inside jokes and lots of F-bombs. 6. "Star Wars: The Last Jedi" (2017) "Star Wars: The Last Jedi." LucasFilms Opening weekend: $220 millionRey (Daisy Ridley) hones her new Jedi powers under the guidance of Luke Skywalker (Mark Hamill), who is unsettled by her abilities. 5. "Star Wars: The Force Awakens" (2015) "Star Wars: The Force Awakens." Walt Disney Studios Motion Pictures Opening weekend: $247.9 millionThree decades after the Empire's defeat, a new threat arises in the militant First Order. A scavenger named Rey gets caught up in the Resistance's search for the missing Luke Skywalker. 4. "Avengers: Infinity War" (2018) "Avengers: Infinity War." Marvel Opening weekend: $257.7 millionThe Avengers and their allies must be willing to sacrifice all in an attempt to defeat the powerful Thanos. 3. "Spider-Man: No Way Home" (2021) "Spider-Man: No Way Home." Sony/Marvel Opening weekend: $260 millionSpider-Man (Tom Holland) finds himself battling old and new villains with the help of the Spider-Man (Tobey Maguire and Andrew Garfield) in the multiverse. 2. "Avengers: Endgame" (2019) "Avengers: Endgame." Disney/Marvel Studios Opening weekend: $357 millionAfter Thanos did the snap felt around the world, the remaining Avengers come together to set everything right. 1. "Spider-Man: Brand New Day (2026) "Spider-Man: No Way Home." Sony/Marvel Opening weekend: $360 millionWith his friends no longer knowing who he is, Peter Parker goes even deeper into his crime-fighting ways. He'll need to heal himself before he takes on a major villain. Read next Jason Guerrasio is an award-winning entertainment correspondent at Business Insider and has covered various aspects of the film industry for over two decades. On the site, his reporting can range from what's going on behind the scenes at some of the biggest companies in Hollywood, colorful interviews with some of the most well-known names in entertainment, and exploring the darker side of the industry.In 2020, Jason received the New York Press Club award and Los Angeles Press Club award for his story on the rise and fall of MoviePass. It has since been made into the Emmy-nominated HBO documentary "MoviePass, MovieCrash."Previous to BI, Jason was the managing editor at Filmmaker Magazine, one of the leading publications in the independent film industry. He's also written for numerous publications over the years, including Vanity Fair, Esquire, Rolling Stone, Vulture, Variety, and indieWire.Popular ArticlesMary Carole McDonnell built a true-crime empire. Then the FBI came for her. Growing up Marvel: The tormented life of Stan Lee's child, JC LeeA bullet. A legend. A lie. Bufford Pusser killed his wife, authorities say. 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