Review of Obesity and Cancer

To the Editor Dr Shen and colleagues provided a timely and useful Review of the biological links between obesity and cancer. They appropriately identified hepatobiliary cancer as one of the malignancies most strongly associated with excess adiposity and include liver cancer among obesity-related cancers. Yet liver cancer may be harder to accommodate within a broad pan-cancer framework because the pathway from obesity to hepatocarcinogenesis is often mediated less by body size itself than by chro...