Karla Souza To Star In ‘Grey’s Anatomy’ Texas Spinoff

Karla Souza (How to Get Away with Murder, 56 Days) has been cast as a lead in ABC‘s new Grey’s Anatomy spinoff set in West Texas. She is the first actor to join the untitled 20th Television studio series from executive producers Shonda Rhimes, Betsy Beers, Meg Marinis, and Ellen Pompeo. Created by Grey’s Anatomy creator Rhimes and current showrunner Marinis, the new show is described as an edgy drama about a team at a rural West Texas medical center — the last chance for care before miles of nowhere. Souza will play Carolina “Lina” Hall, a haunted and cynical doctor in her 40s who runs a medical center in a small town in West Texas. The project reunites Souza with Rhimes and Beers after the actress starred in the hit ABC series How to Get Away with Murder, executive produced by the duo via Shondaland. Watch on Deadline As Deadline reported last week, the untitled new Grey’s Anatomy spinoff will be the first series to shoot outside of Los Angeles in the franchise’s 23-year history. Unable to secure a California tax credit, the offshoot, currently in pre-production, now calls Albuquerque, New Mexico home. Production is expected to begin in early 2027, around February/March, sources tell Deadline, for a premiere during the 2027-28 season. Shondaland has a lengthy history of shooting in California, including the Seattle-set Grey’s Anatomy and its previous spinoffs, Private Practice and Station 19, as well as two series set in Washington, D.C., ABC’s Scandal and Netflix’s The Residence, the Philadelphia-set ABC drama How to Get Away With Murder, and the network’s The Catch. Souza is perhaps best known for playing Laurel opposite Viola Davis in ABC’s How to Get Away with Murder. Most recently, she starred as a series regular in Prime Video’s 56 Days opposite Dove Cameron and Avan Jogia, and prior to that, she played Marina on ABC’s Home Economics and starred opposite Jamie Foxx in Netflix’s Day Shift. She also recently received two International Emmy Awards for producing and starring in Dive (aka La Caida) for Prime Video. Souza is repped by Gersh, Untitled and Gang Tyre.