Ali Hewson, like many women, was unprepared for the intensity of perimenopause. “I initially thought I would just grin and bear it, as my mother did,” she says. But the symptoms piled on: brain fog, hot flashes, mood swings, dryness, exhaustion. “One minute you are happy and content, then suddenly you are anxious and irritable followed by intense heat and sweating,” Hewson says. At their worst, her hot flashes were happening hourly. The symptoms began to take a toll on her rich and...