Conventional Wisdom on CGRP in Migraine Challenged

A new study suggests that plasma levels of calcitonin gene-related peptide (CGRP) might not be as effective as previously thought for diagnosing migraines, since they were found to be lower in migraine sufferers compared to healthy individuals. This finding challenges the conventional view that CGRP levels vary based on migraine subtype, attack status, or preventive treatment use. Such a discovery could significantly impact how migraines are diagnosed and treated, potentially steering researchers and clinicians toward alternative biomarkers or diagnostic methods.