Common constipation drug may help clear depression brain fog

Researchers discovered that a commonly used constipation drug, prucalopride, could potentially alleviate "brain fog" associated with depression. In a small trial, those who took the drug for a week showed marked improvements in memory, attention, and cognitive speed compared to those given a placebo. The drug works by targeting a serotonin receptor present in both the gut and the brain, and it appears to have minimal side effects. This finding could be a major breakthrough for individuals struggling with the cognitive impairments that often accompany depression.