Christina Applegate details debilitating health struggles after MS misdiagnosis: ‘This is what I’m still living with’

See more of our coverage in your search results. Christina Applegate revealed she’s dealing with debilitating mobility issues after her multiple sclerosis misdiagnosis. “I actually timed it today. It took me ten minutes to be able to move off my pillow and get out of the bed and stand up,” the “Dead to Me” actress explained on Tuesday’s episode of her “MeSsy” podcast, which she co-hosts with “Sopranos” alum Jamie-Lynn Sigler, who has MS. Applegate, 54, said that when she got up, she “almost couldn’t walk to the bathroom, and now a walker is sitting next to my bed because of what’s going on.” Christina Applegate (seen here) detailed her debilitating mobility issues after her MS misdiagnosis. Emma McIntyre/Getty Images for SiriusXM Applegate (pictured here at the 2024 Emmys) revealed it took her ten minutes to move off her pillow and get out of bed. WireImage “I don’t know what’s going on,” she stated. “This is what I am still living with.” The Emmy Award winner said she’s “never” had mobility issues this bad, and was always “able to sit up” on her own. “So this is what I said when things are getting worse,” she shared. “Or they’re just new. Something new is happening. It took 10 minutes just to sit my head up, just to move without excruciating pain and weakness.” The actress (seen here during a “GMA” interview) explained that she “almost couldn’t walk to the bathroom” and now she has a walker next to her bed. ABC News Applegate (pictured above with podcast co-host Jamie-Lynn Sigler) said she’s “never” had mobility issues that were this bad. ABC News Last week, Applegate shockingly revealed that doctors told her she doesn’t have MS, after spending the last five years detailing her assumed battle with the chronic autoimmune disease. “[My doctor] came into my room and said, ‘Congratulations, you don’t have MS,’” she recalled on the Oct. 20 episode of her podcast. “I was, like, not happy at all. Everybody else was so happy.” The mom of one called her misdiagnosis a “mindf—k” and said she’s still suffering from debilitating symptoms. “I haven’t gotten better, Jamie! If anything, I’ve gotten worse,” she said last week. “So I’m back at square one where I don’t know what’s going on with me.” Applegate (seen here at her Hollywood Walk of Fame star ceremony in 2022) explained that her next step is to visit a rheumatologist and then “go from there.” Getty Images The Emmy Awards winner (seen here at the 2023 Critics Choice Awards) admitted going to the doctor “overwhelms” her because she struggles to move around. Getty Images for Critics Choice Association Want more celebrity and pop culture news? Start your day with Page Six Daily. Thanks for signing up! In her new podcast episode, Applegate explained that her next step is to visit a rheumatologist, a doctor who specializes in treating diseases that affect the joints, muscles and bones. “And you know, we’ll go from there,” she said. “If that doesn’t come with any kind of results, then we’re going to go to a different specialist and then a different specialist.” Applegate admitted the doctor’s visits “start to overwhelm me, because getting around and going to offices and s–t is a lot.” Applegate (seen here at the 2020 Critics Choice Awards) revealed her MS misdiagnosis on her podcast last week. Getty Images for Critics Choice Association Applegate (seen here at a charity event in April 2025) promised the MOS community that she’s still her “warrior” despite the misdiagnosis. Getty Images She added, “I think I just have to go, all right, one step at a time. And hoping there are answers out there.” Elsewhere in the episode, the “Married…with Children” star assured the MS community that “even though I don’t have this disease,” she’s still their “warrior.” “I’m still going to speak out on your behalf forever and ever,” Applegate promised. “I still feel like part of this community and no matter what, I love you.” Community Guidelines Welcome to the Page Six Community! Our community is about connecting people through open and thoughtful conversations. We want our readers to share their views and exchange ideas in a safe space. In order to do so, we've created a simple set of rules that will improve your experience. Simply put, keep it civil. 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