Buckeyes seek revenge for Big Ten title game loss: Polymarket futures odds and model projections before Indiana

Ohio State's Julian Sayin throws against Indiana's Stephen Daley during the second half of the Big Ten championship NCAA college football game in Indianapolis, Saturday, Dec. 6, 2025.APBy Michael Rochman | Advance LocalLast season, the Ohio State Buckeyes looked on track to win the Big Ten before a scrappy Indiana Hoosiers team secured a 13-10 victory, extending the Buckeyes’ conference championship drought another season.Saturday, October 17, 2026, No. 4 Ohio State hits the road to take on the No. 5 Indiana Hoosiers at Memorial Stadium for a chance at revenge. Kickoff is scheduled for 12:00 p.m. EST, and the game is set to air on FOX.As a top-five matchup, this is no doubt one of the biggest games on the Buckeyes’ schedule. ESPN’s playoff predictor gives both teams a greater than 75% chance of making the College Football Playoff. Still, neither program wants to let the chance of a major victory slip.As kickoff draws closer, we’ve received more updates regarding the injury status of both teams. Indiana has a fairly clean injury report, as RB Khobie Martin (forearm) is doubtful, and TE Andrew Barker (unknown) is questionable. Ohio State will be missing RB Ja’kobi Jackson (ankle), OG Austin Siereveld (non-football), while WR Brock Boyd is doubtful. Here is a full view of the latest availability report shared by the Big Ten:As a result, the data analysts at Dimers updated their Indiana-Ohio State score prediction after conducting new simulations that took into account every element of matchup data.The results of Dimers’ simulations were compared to updated sportsbook odds to compile the data-driven Indiana-Ohio State preview below.Indiana vs. Ohio State betting previewExplore the interactive widget below to discover the current spread, over/under, and moneyline betting odds and probabilities for the Indiana-Ohio State matchup at Memorial Stadium.This prediction and best bet for Saturday’s CFB matchup between the Hoosiers and Buckeyes is from Dimers.com, a dependable source for sports betting predictions.Check out all the important details on tonight’s game, as well as the best odds sourced from the top sportsbooks in the country.Game detailsKey information on this Indiana-Ohio State matchup, including where the game is and what time it kicks off.Teams: Indiana Hoosiers vs. Ohio State BuckeyesDate: Saturday, October 17, 2026Time: 12:00 p.m. ESTLocation: Memorial Stadium (Bloomington, Ind.)NCAAF Standings: Check the latest updates to the official CFB standings.CFB Saturday OddsPolymarket is one of the best platforms to trade on ahead of kickoff. Here is the currently outlook of key markets for the Buckeyes-Hoosiers CFB Game.Spread: Indiana +3.5 (56¢), Ohio State -3.5 (45¢)Moneyline: Indiana (42¢), Ohio State (59¢)Total: Over/Under 50.5 (50¢/51¢)Win probabilityTeamExpert %Indiana Hoosiers41.0%Ohio State Buckeyes59.0%Expert prediction: Indiana vs. Ohio StateUsing trusted data analysis and machine learning, the experts at Dimers have performed 10,000 simulations of Saturday’s Indiana vs. Ohio State matchup.According to Dimers’ popular predictive analytics model, Ohio State is more likely to beat Indiana at Memorial Stadium. This prediction is based on the model giving the Buckeyes a 59.0% chance of winning the game, a 3.2% decrease from when we checked this data earlier this week.Furthermore, Dimers predicts that Ohio State at -3.5 has a 49.3% chance of covering the spread. The over/under total of 50.5 points leans 51.5% toward the over.As always, these predictions and probabilities are accurate at the time of publication but are subject to change.Indiana vs. Ohio State best betOur top pick for Saturday’s game is to bet on Over 50.5 points (50¢). With around a 51.5% probability, it offers good confidence to capitalize on ahead of the showdown.This betting advice is formulated through world-class modeling and valuable betting intelligence, designed to help you make more informed investments.Win prediction for Hoosiers vs.BuckeyesDimers’ predicted final score for the Ohio State vs. Indiana game on Saturday has the Buckeyes winning 27-24.This expert prediction is based on each team’s average outcome following 10,000 game simulations, offering a glimpse into the potential outcome.CFB Saturday: Buckeyes vs. HoosiersGet ready for Saturday’s Week 7 CFB clash between the Indiana Hoosiers and the Ohio State Buckeyes at Memorial Stadium, kicking off at 12:00 PM EST. Plenty of attention will be put toward this game as the Buckeyes being dealt a second loss could start to raise doubt for the team’s postseason chances, while Indiana struggled last weekend in a 20-17 escape against Nebraska.Both teams will be feeling the heat ahead of kickoff for a matchup that most college football fans across the country should be tuned in for.CFB picks and prediction market props add an enjoyable dimension to the biggest weekend on the American sports calendar.All CFB predictions in this article are derived from 10,000 data-driven simulations of the Buckeyes vs. Hoosiers matchup and are accurate at the time of publishing. It is important to gamble responsibly and seek trustworthy sources for the latest and most accurate information when making online betting choices.CFB Prediction market sign-up bonusesHoosiers and Buckeyes fans across the US can use prediction markets to trade on the CFB season as an alternative to standard betting. Here are the top options and available promo codes for new users:PlatformNFL/CFB Eligible?October ’26 Sign-Up BonusVerified Promo CodesPolymarketYes$50CUSE, MASS, OREGON, SILIVE, CLEVEKalshiYes$25SYRACUSE, OREGONLIVE1, MASSLIVE1, SILIVE, CLEVELANDNovigYes$50SYRACUSE, OREGON, MASSLIVE, CLEVELANDPolymarket is a prediction market platform, not a sportsbook. Users trade positions on event outcomes using real funds. Must be 18+ and eligible under applicable law. Trading involves risk. Prices reflect the market at time of writing and are subject to change. All times listed are EDT.College football Kalshi promo code “CLEVELAND55” extends $55 Ohio State-Indiana bonusNew Polymarket promo code “CLEVE” updates $25 referral promo in time for Ohio State-IndianaPolymarket referral code “CLEVE” extends $25 bonus in OH for Seahawks-Broncos tonightNFL Kalshi promo code “CLEVELAND55” updates $55 deal for Seahawks vs. BroncosMLB Kalshi promo code “CLEVELAND55” launches $55 Rays-Guardians Game 3 bonusLearn more about our gaming editorial staff.If you or a loved one has questions and needs to talk to a professional about gambling, call the Ohio Problem Gambling Helpline at 1-800-589-9966 or the National Council on Program Gambling Helpline (NCPG) at 1-800-522-4700 or visit 1800gambler.net for more information. 21+ and present in Ohio. Gambling problem? Call 1-800-Gambler. 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