Boehringer Ingelheim launches SCOVELLA® in Great Britain, the first approved therapy for insulin dysregulation in horses, a main cause of laminitis

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Postmedia has not reviewed the content. by GlobeNewswire Boehringer Ingelheim launches SCOVELLA® in Great Britain, the first approved therapy for insulin dysregulation in horses, a main cause of laminitisAuthor of the article:Ingelheim, Germany GNWIngelheim, Germany, and Bracknell, United KingdomTHIS CONTENT IS RESERVED FOR SUBSCRIBERS ONLYSubscribe now to read the latest news in your city and across Canada.Exclusive articles from Barbara Shecter, Joe O'Connor, Gabriel Friedman, and others.Daily content from Financial Times, the world's leading global business publication.Unlimited online access to read articles from Financial Post, National Post and 15 news sites across Canada with one account.National Post ePaper, an electronic replica of the print edition to view on any device, share and comment on.Daily puzzles, including the New York Times Crossword.SUBSCRIBE TO UNLOCK MORE ARTICLESSubscribe now to read the latest news in your city and across Canada.Exclusive articles from Barbara Shecter, Joe O'Connor, Gabriel Friedman and others.Daily content from Financial Times, the world's leading global business publication.Unlimited online access to read articles from Financial Post, National Post and 15 news sites across Canada with one account.National Post ePaper, an electronic replica of the print edition to view on any device, share and comment on.Daily puzzles, including the New York Times Crossword.REGISTER / SIGN IN TO UNLOCK MORE ARTICLESCreate an account or sign in to continue with your reading experience.Access articles from across Canada with one account.Share your thoughts and join the conversation in the comments.Enjoy additional articles per month.Get email updates from your favourite authors.THIS ARTICLE IS FREE TO READ REGISTER TO UNLOCK.Create an account or sign in to continue with your reading experience.Access articles from across Canada with one accountShare your thoughts and join the conversation in the commentsEnjoy additional articles per monthGet email updates from your favourite authorsSign In or Create an AccountSCOVELLA® is the first therapy specifically developed and approved for the treatment of hyperinsulinemia in insulin-dysregulated horses and ponies1, targeting the key underlying driver of laminitis.²Studies showed that SCOVELLA® rapidly and significantly reduces hyperinsulinemia with effects showing within days of starting treatment.4,6Laminitis is one of the most significant causes of pain and disability in horses, with one-third of affected horses euthanized within a year of diagnosis.³Boehringer Ingelheim launches SCOVELLA® (velagliflozin oral solution), the first therapy developed and licensed in Great Britain for the treatment of insulin dysregulation (ID) in horses and ponies.1Get the latest headlines, breaking news and columns.By signing up you consent to receive the above newsletter from Postmedia Network Inc.A welcome email is on its way. If you don't see it, please check your junk folder.The next issue of Top Stories will soon be in your inbox.We encountered an issue signing you up. Please try againAffecting an estimated one in five horses, insulin dysregulation is recognized as the primary underlying cause of laminitis.² One-third of horses diagnosed with laminitis are euthanised within a year of diagnosis.³ A UK cohort study estimated that around one in ten horses and ponies experiences at least one episode of laminitis each year.5“Laminitis is one of the most common and welfare-impacting conditions we face in equine practice. Until recently, treatment and prevention options have been limited. The availability of a therapy specifically developed and approved for horses represents an important advance and provides veterinarians with a new option to manage insulin dysregulation, the condition that underlies the majority of cases of laminitis, ” said Professor Andy Durham BVSc BSc CertEP DEIM DipECEIM MRCVS, RCVS and European Specialist in Equine Internal Medicine, Liphook Equine Hospital.The risk of laminitis increases in direct correlation with circulating insulin concentrations, making effective insulin control an important therapeutic objective. SCOVELLA® is the first licensed equine-specific SGLT-2 inhibitor developed for the treatment of hyperinsulinemia in insulin-dysregulated horses and ponies that are not responsive to changes in husbandry and exercise regimens, available as an easy-to-dose oral liquid. By lowering elevated insulin concentrations, it helps veterinary surgeons address the key driver of laminitis. Insulin dysregulation is estimated to account for over 90% of all laminitis cases.²The development of SCOVELLA® was supported by an extensive body of clinical research. The therapy rapidly and significantly reduces hyperinsulinemia with effects showing within days of starting treatment.4,6 In a clinical dietary challenge trial, none of the animals treated with SCOVELLA® developed clinical laminitis, compared with 38% of untreated controls.6“Laminitis is a devastating diagnosis for both horse owners and horses because of the pain it can cause and the potentially serious consequences for affected horses. SCOVELLA® is the result of 15 years of our research focused on addressing the disease at its source and reflects our commitment to advancing innovation in equine health where unmet need remains high,” said Saskia Kley, Global Head of Equine at Boehringer Ingelheim.This advertisement has not loaded yet.This advertisement has not loaded yet, but your article continues below.SCOVELLA® will be available to prescribing veterinary surgeons in Great Britain from September 2026, debuting officially at BEVA (British Equine Veterinary Association) Congress. Boehringer Ingelheim plans to bring the treatment to other markets in the future.“We are excited to introduce this global innovation to the equine veterinarian community in Great Britain first, reinforcing our position as the leader in equine medicine and welfare. SCOVELLA® gives vets and horse owners a high treatment confidence by providing rapid and sustained insulin reduction4,6, addressing the main cause of laminitis,” said Craig Beck, Head of Animal Health UK and Ireland, Boehringer Ingelheim. “To support vets, we’re also rolling out a comprehensive package of support, including educational materials for vets to assist practices in successfully managing laminitis cases.”Marketing authorization granted as a limited marketing authorization under Article 26(1)(b) of the UK Veterinary Medicines Regulations (April 2026). Indication: For the treatment of hyperinsulinaemia in insulin-dysregulated horses and ponies not responsive to changes in husbandry and exercise regimen. See the VMD Product Information Database.Karikoski, N. P., Horn, I., McGowan, T. W., & McGowan, C. M. (2011). The prevalence of endocrinopathic laminitis among horses presented for laminitis at a first-opinion/referral equine hospital. Domestic animal endocrinology, 41(3), 111-117.Luthersson, N., Mannfalk, M., Parkin, T. D., & Harris, P. (2017). Laminitis: risk factors and outcome in a group of Danish horses. Journal of Equine Veterinary Science, 53, 68-73.Thane, K., Voth, R., Klee, R., Warnken, T., Chukwu, V., & Frank, N. (2025). Effects of the sodium-glucose cotransporter-2 inhibitor velagliflozin on insulin concentrations in horses with insulin dysregulation. Journal of Veterinary Internal Medicine, 39(6), jvim70256.Pollard, D., Wylie, C. E., Newton, J. R., & Verheyen, K. L. P. (2019). Incidence and clinical signs of owner‐reported equine laminitis in a cohort of horses and ponies in Great Britain. Equine Veterinary Journal, 51(5), 587-594.Meier, A., Reiche, D., de Laat, M., Pollitt, C., Walsh, D., & Sillence, M. (2018). The sodium-glucose co-transporter 2 inhibitor velagliflozin reduces hyperinsulinemia and prevents laminitis in insulin-dysregulated ponies. PLoS One, 13(9), e0203655.About Boehringer Ingelheim – Animal Health businessBoehringer Ingelheim provides innovation for preventing and treating diseases in animals. The company offers a wide range of vaccines, parasite-control products, and medicines for pets, horses, and livestock to veterinarians, animal owners, farmers, and governments. As a leader in animal health, Boehringer Ingelheim values that the health of humans and animals is deeply connected and strives to have influence on people, animals, and society. Learn more at www.boehringer-ingelheim.com/animal-health.About Boehringer IngelheimBoehringer Ingelheim is a biopharmaceutical company active in both human and animal health. As one of the industry’s top investors in research and development, the company focuses on developing innovative therapies that can improve and extend lives in areas of high unmet medical need. Independent since its foundation in 1885, Boehringer takes a long-term perspective, embedding sustainability along the entire value chain. Our approximately 54,300 employees serve over 130 markets to build a healthier and more sustainable tomorrow. Learn more at www.boehringer-ingelheim.com. Notice for the Postmedia NetworkThis website uses cookies to personalize your content (including ads), and allows us to analyze our traffic. Read more about cookies here. By continuing to use our site, you agree to our Terms of Use and Privacy Policy.